Esidrix - diuretic agent used for diseases of the lungs, liver, kidneys and heart to reduce swelling, which was caused by fluid retention and salts in the body. Saluretics Esidrix's action is based on its ability to increase the urinary excretion of potassium, magnesium and sodium. Use of the drug can significantly reduce the reabsorption (reverse absorption) of liquid, sodium and chlorine ions in the distal tubule. Esidrix, acting on distal tubules, reduces the excretion of calcium ions, which respectively prevents formation in the kidney of calcium stones. Use of the drug enhances renal concentrating ability, oppression susceptibility to the effects of the vascular wall mediators involved in the transmission of nerve impulses. Esidrix possesses hypotensive (pressure reducing) effect, but also reduces polyuria (increased urine production) to patients with diabetes insipidus. Furthermore, Esidrix is able in some cases to reduce intraocular pressure provoked by closed-angle glaucoma.
Indications for use:
Esidrix's applying is recommended for: hypertension; diabetes insipidus; congestive heart failure; nephritis (an inflammatory disease of the kidney) and nephrosis (secondary kidney disease); cirrhosis with ascites edematous syndrome and portal hypertension; pregnancy complications: edema, nephropathy (kidney disease), eclampsia (high blood pressure is critical); edema of various origins; subcompensated form of glaucoma; preventing the formation of stones.
Instructions for use:
Esidrix tablets are intended for peroral use. It is advised to take Esidrix in the morning after eating, not chewing and grinding. Daily dose corresponding to 25-50 mg of the drug is prescribed to aim reducing of blood pressure. Hypotensive effect was observed after 3-4 days, but sometimes in order to achieve the desired result may need 3-4 weeks. Edema treatment requires reception of 1-4 tablets of Esidrix (25-100 mg) once per 1-2 days, depending on the response and state of the patient. Patients suffering nephrogenic diabetes insipidus need to take 50-150 mg of Esidrix in several steps until reducing of thirst and polyuria, then dose may be reduced. Elderly patients usually take 12.5 mg, 1-2 times per day. Children's (older than 3 years) daily dose is determined by multiplying of 1 mg on the body's weight and is taken once a day.